Translational research based on molecular craniofacial developmental biology and development of related clinical activities
|Leader||Ichiro Takahashi, Kyushu University|
|Researcher||Yoshihide Mori, Kazuaki Nonaka, Naoto Haruyama, Haruyoshi Yamaza, Fumie Terao, Keigo Yoshizaki (Kyushu Univeristy)|
|Term||April 2016－March 2017|
Because the inborn specific abnormality that the phenotype appears in a face and the oral cavity affects chewing, speech, breathing as well as swallowing function, a life support function of the patient. The specific and strange feature of craniofacial anomaly in the face affects a socio-psychological activity leading the reduction of patients’ quality of life remarkably. The cleft lip and/or cleft palate that are representative inborn specific abnormality show a phenotype on face. The occurrence rate ranges from one of 500 births to one of 700 births in the world.